Mururé es un árbol de 15 a 25 m de altura, la savia del árbol es de látex de color blanco a rosa claro. Ampliamente distribuida en la selva de la cuenca amazónica.
Nombre botánico: Brosimum acutifolium
Familia: Moráceas
Parte utilizada: corteza
Nombres populares: manichi, morure, muira-piranga, murare, murure, mururi, ahua jonra, amapá doce, bururé, congona, leche-caspi, quecho, tamamuri, tauni, urupi.
Properties:
Antirheumatic
Anti-inflammatory
Antifungal
Anthelmintic
Antineoplastic
Analgesic,
Anti-syphilitic,
Purification,
Stimulating the nervous and muscular system.
• Aphrodisiac
Request:
• for the treatment of rheumatism, arthritis, including rheumatoid arthritis;
• to relieve pain and inflammation (eg muscle aches, injuries, headaches, etc.);
• with gastric ulcer (Helicobacter Pylori), gastritis, colitis and other gastrointestinal diseases;
• with candidiasis (candidiasis), including lesions of the skin and nails;
• antineoplastic;
• in the treatment of syphilis.
Biological activity and clinical research.
Properties and actions confirmed by laboratory tests:
Antibacterial (eg Bacillus and Staphylococcus, Helicobacter Pylori), antifungal (Candida Albicans, etc.), anti-inflammatory (including autoimmune inflammation), antitumor, antileukemic, cytotoxic, PKA and PKC inhibitor.
Properties and actions confirmed by traditional use:
analgesic, anthelmintic, antianemia, anti-inflammatory, antirheumatic, antisiphilitic, aphrodisiac, appetite stimulant, cleansing, tonic and anthelmintic.
In 2003, Brazilian researchers reported that a crude extract of murure bark produced a persistent and repeatable effect of reducing inflammation in laboratory rats caused by several factors. They also reported that mururins A and B, which are part of the cortex, have the ability to inhibit protein kinases C (PKC) and A (PKA).
Protein kinases have a significant effect on cellular activity. They regulate the cell cycle, the growth and differentiation of cells, as well as the processes of self-destruction at the cellular level (apoptosis). Disruptions in the work of protein kinases lead to various pathologies, including the appearance of autoimmune diseases accompanied by autoimmune inflammation and the appearance of certain types of cancer, including some lines of leukemia.
Drugs that inhibit specific protein kinases are being developed to treat these diseases, and mururé bark extract can be classified as such a natural product.
Researchers from Cornell University (USA) reported that murure bark extract has been shown to be antibacterial against common bacteria such as Bacillus and Staphylococcus. The same study showed that the substances in the bark are active against Helicobacter Pylori (a bacterium that causes peptic ulcer), as well as Candida Albicans (a yeast-associated fungus that causes candidiasis of the oral cavity, genitals, digestive tract, and skin. and nails).
Chemical composition of the bark of mururé (Brosimum acutifolium Huber).
Murure bark contains flavones, flavonoids, lignans, phenylpropanoids, benzoids, and steroids. In addition to these substances, a number of chemical compounds have been found in the composition of the crust, which are currently unknown to scientists or little studied. These include six compounds collectively called acutifolins and thirteen combined called brosimacutins.
Chemicals found in the bark of mururé (Brosimum acutifolium Huber):
acutifolines AF, brosimactins AM, brosimine A and B, (-) 5-O-beta-D-xylopyranoside epicatechin, (-) epicatechin, (-) liquiditigenin, (-) naringenin, bufotenin, 3′-7-dihydroxy-4 ‘-methoxy-flavan, 4′-hydroxy-7-8- (2’ ‘-2’ ‘-dimethyl-pyranflavan), 4′-7-dihydroxy-flavan, 4’-7-dihydroxy-8-preniflavan, 4 ‘-hydroxy-7-8- (3’ ‘- hydroxy-2’ ‘- 2’ ‘- dimethylpyranflavan), beta-sitosterol, coniferaldehyde, dihydroconiferyl, hydroxyloncocarpine, icarizide E-3 aglycone, isohydroxycordoine, isobavaquine, iso-laricisenol, iso-liquiditygenin, liquiditrigenin, luteolin, mururin AC, protocatechinic acid, stigmasterol, and syringaldehyde.
Method of preparation and use:
Infusion: pour 1 teaspoon of powder into 1 liter of boiling water, infuse overnight. Take 3-4 times a day on an empty stomach or instead of drinking during the day.
Tincture: 150 g of powder, pour 1 liter of vodka or brandy, sweeten with honey. Insist for 7 days in a cool dark place. Take 1 tablespoon 3 times a day on an empty stomach.
Powder – 1 g each. 3 times a day on an empty stomach.
NOTE: Do not use in pregnant women. Taking the plant requires excluding spices, spicy foods, pork, and alcoholic beverages from the diet.
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