Properties and actions confirmed by laboratory tests:

Antibacterial (eg Bacillus and Staphylococcus, Helicobacter Pylori), antifungal (Candida Albicans, etc.), anti-inflammatory (including autoimmune inflammation), antitumor, antileukemic, cytotoxic, PKA and PKC inhibitor.

Properties and actions confirmed by traditional use:

analgesic, anthelmintic, antianemia, anti-inflammatory, antirheumatic, antisiphilitic, aphrodisiac, appetite stimulant, cleansing, tonic and anthelmintic.

In 2003, Brazilian researchers reported that a crude extract of murure bark produced a persistent and repeatable effect of reducing inflammation in laboratory rats caused by several factors. They also reported that mururins A and B, which are part of the cortex, have the ability to inhibit protein kinases C (PKC) and A (PKA).

Protein kinases have a significant effect on cellular activity. They regulate the cell cycle, the growth and differentiation of cells, as well as the processes of self-destruction at the cellular level (apoptosis). Disruptions in the work of protein kinases lead to various pathologies, including the appearance of autoimmune diseases accompanied by autoimmune inflammation and the appearance of certain types of cancer, including some lines of leukemia.

Drugs that inhibit specific protein kinases are being developed to treat these diseases, and mururé bark extract can be classified as such a natural product.

Researchers from Cornell University (USA) reported that murure bark extract has been shown to be antibacterial against common bacteria such as Bacillus and Staphylococcus. The same study showed that the substances in the bark are active against Helicobacter Pylori (a bacterium that causes peptic ulcer), as well as Candida Albicans (a yeast-associated fungus that causes candidiasis of the oral cavity, genitals, digestive tract, and skin. and nails).